I played Hockey when I was younger and always remembered having Oranges at half-time, wearing them like gum shields afterwards, at that time we were really after the sugar as sports drinks hadn’t really been invented, actually neither had gum shields. We realise now that vitamin C is an immune-supporting, flu stifling necessity. But there is far more to this nutrient than fighting off a cold. From Brain health to collagen production here’s what you need to know about vitamin C, and why getting the right dose matters more than ever.

What the Regulators Say: FSA and EFSA-Approved Claims
According to the European Food Safety Authority (EFSA), which governs health claims in the EU (and remains influential for UK brands via the FSA), vitamin C is allowed to carry the following approved claims:
- Contributes to the normal function of the immune system
- Contributes to normal collagen formation for skin, bones, cartilage, and gums
- Contributes to the normal function of the nervous system
- Helps reduce tiredness and fatigue
- Protects cells from oxidative stress (antioxidant activity)
- Increases iron absorption
- Regenerates the reduced form of vitamin E
In short: vitamin C plays a key role in everything from immunity and energy to skin, joints, and brain health — but only if you’re getting enough of it consistently.
Vitamin C and Brain Health: More Than Just an Immune Booster
Vitamin C has long been the go-to nutrient for immunity — the first thing we reach for when we feel a cold coming on. But emerging research suggests its role in the body is far broader and far more essential — especially when it comes to the Brain.
Unlike some vitamins that play supporting roles, vitamin C is deeply embedded in how the brain functions on a daily basis: from producing neurotransmitters to protecting against cellular damage. And yet, it’s often overlooked in conversations about cognitive health.
Antioxidant Protection Where It Matters Most
The brain is highly active, oxygen-hungry, and lipid-rich — a perfect storm for oxidative stress. That’s where vitamin C comes in. As one of the body’s most powerful water-soluble antioxidants, vitamin C protects neurons from oxidative damage caused by free radicals.
Oxidative stress is one of the major contributors to age-related cognitive decline, neuroinflammation, and diseases like Alzheimer’s. By neutralising free radicals, vitamin C helps preserve cellular integrity and slow down degenerative processes.
Fuel for Neurotransmitter Production
Vitamin C is also a key co-factor in the production of neurotransmitters — the chemical messengers that regulate mood, focus, memory, and alertness.
In particular, it’s involved in the synthesis of:
- Dopamine, associated with motivation, pleasure, and reward
- Norepinephrine, which supports attention and energy
- Serotonin, linked to mood balance and emotional regulation
Low vitamin C levels can impair these pathways, potentially leading to symptoms like brain fog, low mood, fatigue, or poor focus — especially in older adults.
Found in Abundance in the Brain
The brain maintains some of the highest concentrations of vitamin C in the body, particularly in areas responsible for memory and decision-making like the hippocampus and cerebral cortex. This suggests just how vital the nutrient is for brain health — even during deficiency, the brain works to conserve it.
Mood, Stress, and Mental Energy
Vitamin C also plays a role in the body’s stress response. It can lower cortisol levels and improve mental strength. In some trials, vitamin C has been shown to reduce fatigue and improve mental clarity in just a couple of weeks.
Backed by Research: Recent Scientific Evidence on Vitamin C and Cognition
A growing body of evidence connects vitamin C status with cognitive performance:
- A 2022 study titled “Relationship between Vitamin C Deficiency and Cognitive Impairment in Older Hospitalised Patients” found that patients with vitamin C deficiency scored lower on cognitive tests, suggesting a strong link between vitamin C status and brain function. Read it here
- A 2022 meta-analysis, “A Quantitative Meta-Analysis of Vitamin C in the Pathophysiology of Alzheimer’s Disease”, concluded that vitamin C deficiency is involved in Alzheimer’s progression and that supplementation may play a role in prevention and treatment. Read it here
- Another 2022 study, “Vitamin C Deficiency Induces Hypoglycemia and Cognitive Disorder through S-Nitrosylation-Mediated Activation of GSK3β”, explored how vitamin C deficiency may trigger cognitive symptoms via biochemical disruption. Read it here

Natural Sources of Vitamin C
Oranges are iconic when it comes to vitamin C, but they’re far from the highest source — just the most popular.
Here’s a more complete list of vitamin C-rich foods, broken down by category:
Superfruits & Potent Plant Sources
- Camu camu – A superfruit from the Amazon, ~2000–3000 mg per 100g (usually sold as a powdered supplement)
- Acerola cherries – Among the highest sources: up to 1500–2000 mg per 100g
- Rose hips – Up to 426 mg per 100g (commonly used in teas and powdered extracts)
Fruits Rich in Vitamin C
- Guava – ~200–250 mg per fruit
- Blackcurrants – ~180 mg per 100g
- Red bell peppers (raw) – ~190 mg per cup
- Kiwi – ~70 mg per fruit
- Lychees – ~70 mg per 100g
- Papaya – ~60–70 mg per 100g
- Strawberries – ~60 mg per 100g
- Orange – ~70–80 mg per medium fruit
- Pineapple – ~48 mg per cup
- Lemons & limes – ~30–50 mg per fruit
- Mango – ~36 mg per fruit
- Cantaloupe (melon) – ~36–40 mg per cup
- Blueberries & raspberries – ~10–20 mg per 100g
Vegetables Rich in Vitamin C
- Kale (raw) – ~120 mg per 100g
- Brussels sprouts (steamed) – ~50 mg per 100g
- Broccoli (steamed) – ~50 mg per 100g
- Cauliflower – ~50 mg per 100g
- Cabbage (raw or lightly cooked) – ~30–40 mg per 100g
- Spinach (raw) – ~28 mg per 100g
- Peas (fresh) – ~40 mg per 100g
- Sweet potatoes – ~17 mg per 100g
- Tomatoes (especially cherry) – ~20 mg per 100g
- Green beans – ~12–20 mg per 100g
Herbs and Other Plant Sources
- Parsley (fresh) – ~130 mg per 100g (about 10 mg per tablespoon)
- Thyme (fresh) – ~160 mg per 100g
- Chili peppers – 100–240 mg per 100g
Vitamin C is water-soluble and heat-sensitive, so steaming or eating raw preserves more than boiling or frying.
Absorption, NRV, and How Much Is Too Much?
Vitamin C is water-soluble, so your body uses what it needs and passes out the rest — which is why consistent daily intake is more effective than occasional high doses.
- NRV (UK/EU): 80 mg/day for adults
- Optimal range for cognitive and antioxidant support: 100–500 mg/day
- Upper Safe Limit (EFSA): 1000 mg/day
- Toxicity risk: Very low, though doses above 2000 mg/day may cause stomach issues such as bloating or diarrhoea.
Symptoms of deficiency.
Vitamin C deficiency may show up as:
- Fatigue and low energy
- Dry, rough skin
- Poor wound healing
- Bleeding gums or easy bruising
- Irritability and mood changes
In severe cases, it leads to scurvy — a word you’ve probably only heard in pirate movies.
Scurvy.
Scurvy was a genuine medical crisis among sailors in the 17th and 18th centuries. With no access to fresh fruit or vegetables on long voyages, sailors would develop terrifying symptoms: rotting gums, bleeding, fatigue, and eventually death. A scottish naval surgeon James Lind, conducted the first ever clinical trial in 1747. He gave different groups of sailors different treatments — and only those given citrus fruit (Vitamin C) recovered.
The British Navy eventually mandated lime juice on board, earning British sailors the nickname “limeys”.
Conclusion
Vitamin C has a huge impact on modern health – especially brain health and continuous research points to the importance of it in a balanced diet. To support your immunity, reduce fatigue, or take a proactive step toward long-term cognitive wellness, Vitamin C should for part of your balanced diet with supplementation to ensure daily recommended amounts if necessary.
For vitamin C its important to get the right dose every day. It used to be ‘an apple a day’ but maybe we should change that.